Tandem Occlusion Stroke Definition
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Tandem occlusion stroke definition. 6 toshiba stroke and vascular research center university at buffalo state university of new york. Moreover whether the relative resistance to thrombolysis in tandem lesions varies depending on the location of mca clot remains uncertain. Objective acute tandem occlusions of the cervical internal carotid artery and an intracranial large vessel present treatment challenges. Acute ischemic stroke due to tandem occlusions of the extracranial internal carotid artery and intracranial arteries has a poor natural history.
Tandem occlusions tos involving occlusion of the cervical internal carotid artery ica and concomitant intracranial large vessel occlusion lvo of either the intracranial ica and or proximal middle cerebral artery mca have poor response to iv thrombolysis alone 1 and are known to be a predictor of poor outcome after thrombolysis 2 in recent years endovascular thrombectomy has become the standard of care in treating large vessel anterior acute ischemic stroke ais 3 though most. Tandem occlusion which includes cervical internal carotid artery ica severe stenosis occlusion and intracranial occlusion has been a challenge for decades. We aimed to evaluate our single center experience with endovascular treatment of this unique stroke population. 8 jacobs institute buffalo new york.
Tim occlusion has been associated with low recanalization rate after iv tissue plasminogen activator tpa its independent contribution on stroke outcome remains unknown. Iv tpa which was the only available acute stroke treatment before the thrombectomy era achieves recanalization in as low as 4 of patients. Cute tandem occlusion involving the cervical in ternal carotid artery ica with concomitant intra cranial thromboembolism to the intracranial ica terminus or middle cerebral artery mca is estimated to occur in 15 of all cases of large vessel acute ischemic stroke 17 these lesions are challenging to manage endo. Ischemic stroke related to tandem internal carotid and middle cerebral artery tim occlusion is a challenging condition where endovascular treatment evt is an emerging revascularization option.